For this game Galatasaray coach Hamzaoglu will probably prefer to use one more defensive midfielder instead of Yasin at offensive/right wing position and Galatasarays system may turn to be a 4-3-2-1 Podolski and Sneijder supporting Burak Yilmaz at offensive midfield position .
Goalkeeper Muslera is out of form as Mert K mentioned above , he is having problems at long shots interestingly (tall goalkeepers including himself are usually much better in this positions,may have problem with his eyes)
All in all i also think this game is open to a disaster result for Galatasaray but what makes me uncomfortable here is everybody thinking in same direction !
Based on experience i will be waiting for live, we may have an unexpected surprise which is not possible to foresee,a referee who can spoil the party or a very strange coach decision ,can call it a just gut feeling ,saying me not to hurry!
GS's defence is just awful this season. Melo's departure is the key here. Add Chedjou's absence and you have a recipe for disaster. Muslera's form is worth mentioning too.